Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 18/20 | 0.50 |
| ▸ | GSK3B | P49841 | 18/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20775404 | 0.79 | GSK3A (0.45) | GSK3AGSK3BNOTUM | |
| SCHEMBL13824875 | 0.74 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL13825015 | 0.72 | LTK (0.42) | GSK3AGSK3BCHEK1DAPK3ABL1 | |
| SCHEMBL12083969 | 0.71 | LTK (0.38) | GSK3AGSK3BCHEK1DAPK3ABL1 | |
| SCHEMBL25367614 | 0.69 | GSK3A (0.39) | GSK3AGSK3BNOTUM | |
| SCHEMBL20772917 | 0.69 | L3MBTL1 (0.41) | GSK3AGSK3BLTKALKDYRK1B | |
| SCHEMBL13824982 | 0.68 | GSK3A (1.00) | GSK3AGSK3B | |
| SCHEMBL21434271 | 0.68 | GSK3A (0.36) | GSK3AGSK3B | |
| SCHEMBL13824876 | 0.68 | CHEK1 (0.62) | GSK3AGSK3BCHEK1DAPK3ABL1 | |
| SCHEMBL18744225 | 0.67 | ATAD2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150829-A2 | NOBLE TRIAZOLOPYRIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 제일약품주식회사 (KR) | 2012-11-08 | — | — | WO | disclosed |