Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825028 | 0.82 | LTK (0.48) | ALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL13825030 | 0.80 | LTK (0.46) | ALDH1A1KDM4EHPGDCSNK1DPDE3B | |
| SCHEMBL13824909 | 0.74 | LTK (0.50) | CSNK1DPDE3BPDE3A | |
| SCHEMBL13825055 | 0.73 | MEN1 (0.43) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL25101266 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13825031 | 0.70 | GSK3A (0.50) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL4436705 | 0.70 | KDM4E (0.55) | HPGDSALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL14252251 | 0.70 | TSHR (0.65) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL13824906 | 0.69 | RET (0.42) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL28757629 | 0.69 | TSHR (0.58) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150829-A2 | NOBLE TRIAZOLOPYRIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 제일약품주식회사 (KR) | 2012-11-08 | — | — | WO | disclosed |