Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | TKT | P29401 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629593 | 0.81 | TKT (0.33) | S1PR4TKTEGFRCCR1RAB9A | |
| SCHEMBL9181886 | 0.77 | CTRC (0.38) | S1PR4EGFRCCR1RAB9ACCR5 | |
| SCHEMBL25606394 | 0.73 | POLB (0.33) | S1PR4TKTEGFRKMT2A | |
| SCHEMBL3433107 | 0.72 | KMT2A (0.47) | S1PR4EGFRCCR1RAB9ACCR5 | |
| SCHEMBL24094560 | 0.71 | CCR1 (0.36) | S1PR4EGFRCCR1RAB9ACCR5 | |
| SCHEMBL6320237 | 0.71 | ALDH1A1 (0.45) | TKTEGFRCCR1RAB9ACCR5 | |
| SCHEMBL25585826 | 0.71 | CCR1 (0.36) | S1PR4EGFRCCR1RAB9ACCR5 | |
| SCHEMBL31139119 | 0.71 | ALDH1A1 (0.45) | TKTEGFRCCR1RAB9ACCR5 | |
| SCHEMBL10939643 | 0.71 | POLB (0.37) | EGFRLMNACCR1RAB9ACCR5 | |
| SCHEMBL11846794 | 0.70 | TLR8 (0.40) | S1PR4TKTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150829-A2 | NOBLE TRIAZOLOPYRIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | 제일약품주식회사 (KR) | 2012-11-08 | — | — | WO | disclosed |