Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.57 |
| ▸ | CIT | O14578 | 9/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109260 | 0.93 | AAK1 (0.57) | AAK1CITADAM17 | |
| SCHEMBL14400920 | 0.93 | AAK1 (0.57) | AAK1CITADAM17 | |
| SCHEMBL10285898 | 0.93 | AAK1 (0.57) | AAK1CITADAM17 | |
| SCHEMBL13818641 | 0.90 | AAK1 (0.46) | AAK1CIT | |
| SCHEMBL13825529 | 0.87 | AAK1 (0.40) | AAK1TAAR1 | |
| SCHEMBL1109489 | 0.85 | AAK1 (0.58) | AAK1CITTAAR1 | |
| SCHEMBL405324 | 0.84 | AAK1 (0.46) | AAK1 | |
| SCHEMBL1109501 | 0.83 | AAK1 (0.44) | AAK1CITTAAR1 | |
| SCHEMBL401802 | 0.82 | AAK1 (0.44) | AAK1CIT | |
| SCHEMBL403411 | 0.82 | AAK1 (0.44) | AAK1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | AAK1 3950/4885CIT 3670/4885ADAM17 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.