Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 11/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 11/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 11/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 11/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.43 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166827 | 0.81 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8609423 | 0.79 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8612927 | 0.70 | GRIK1 (0.55) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8681277 | 0.70 | GRIA1 (0.76) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8611636 | 0.69 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8611278 | 0.69 | GRIK1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7486337 | 0.68 | GRIK1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610384 | 0.67 | GRIA1 (0.79) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL5167321 | 0.65 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8038353 | 0.65 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773788-B1 | Quinazoline derivatives | NOVARTIS AG (CH) | 2012-11-14 | — | — | EP | disclosed |