Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825844 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL20445748 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL13684505 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL30864790 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL13684506 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL13684727 | 1.00 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL25585142 | 0.95 | POLB (0.44) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL25497599 | 0.84 | RAB9A (0.38) | POLBTDP1APEX1RAB9ANPC1 | |
| SCHEMBL12231001 | 0.80 | POLB (0.48) | POLBTDP1APEX1RAB9AKDM4E | |
| SCHEMBL26718276 | 0.80 | PPM1B (0.49) | POLBTDP1APEX1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357903-B1 | METHOD FOR A CONTINUOUS PRODUCTION OF A Z-CYCLOOCTENE | STICHTING KATHOLIEKE UNIV (NL) | 2020-11-04 | — | — | EP | disclosed |
| EP-3357903-A1 | METHOD AND SYSTEM FOR A CONTINUOUS PRODUCTION OF A Z-CYCLOOCTENE | Stichting Katholieke Universiteit (NL) | 2018-08-08 | — | — | EP | disclosed |
| EP-2522369-A1 | Pretargeting kit, method and agents used therein | Koninklijke Philips Electronics N.V. (NL) | 2012-11-14 | — | — | EP | disclosed |