SCHEMBL25585142

SCHEMBL25585142

O=C(O)[C@@H]1[C@H]2CC/C=C\CC[C@@H]2[C@@H]1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 5/20 0.44
▸ TDP1 Q9NUW8 3/20 0.44
▸ APEX1 P27695 1/20 0.44
▸ RAB9A P51151 2/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.39
▸ TFPI2 P48307 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ GMNN O75496 1/20 0.39
▸ PMP22 Q01453 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ CTDSP1 Q9GZU7 1/20 0.35
▸ GRM8 O00222 1/20 0.33
▸ GRM6 O15303 1/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ GRM3 Q14832 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13684506 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL13825844 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL30864790 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL13825845 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL20445748 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL13684727 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL13684505 0.95 POLB (0.44) POLBTDP1APEX1RAB9ANPC1
SCHEMBL25497599 0.84 RAB9A (0.38) POLBTDP1APEX1RAB9ANPC1
SCHEMBL25585228 0.84 PPM1B (0.49) POLBTDP1APEX1RAB9ANPC1
SCHEMBL25585134 0.84 PPM1B (0.49) POLBTDP1APEX1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365743-A1 FUSED RING MONOMERS PROVIDING FOR CHEMICALLY RECYCLABLE POLYMERS THE UNIVERSITY OF AKRON 2023-11-16 — — US disclosed
US-20230167211-A1 MONOMER ISOMERIZATION AND POLYMER FLUORINATION FOR SUSTAINABLE DEPOLYMERIZABLE POLYMERS THE UNIVERSITY OF AKRON 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167211-A1 MONOMER ISOMERIZATION AND POLYMER FLUORINATION FOR SUSTAINABLE DEPOLYMERIZABLE POLYMERS PFAS, PARG, MFAP1 POLB 210/4885TDP1 1389/4885APEX1 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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