Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.71 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 9/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633884 | 0.98 | MMP3 (0.67) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL27979824 | 0.98 | MMP3 (0.67) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL16000739 | 0.95 | MMP3 (0.62) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL30692092 | 0.93 | ESR1 (0.57) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL5705575 | 0.93 | ESR1 (0.57) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL20323049 | 0.88 | ESR1 (0.61) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL4349120 | 0.88 | MMP3 (0.61) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL13059867 | 0.88 | MMP3 (0.61) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL21667783 | 0.87 | MMP3 (0.83) | MMP3BCL2L1ESR1ESR2MEN1 | |
| SCHEMBL20323043 | 0.87 | MMP3 (0.83) | MMP3BCL2L1ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152366-A1 | ORGANIC IONIC COMPOUNDS, COMPOSITIONS AND ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-11-15 | — | — | WO | disclosed |