Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349120 | 1.00 | MMP3 (0.61) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL30633884 | 0.91 | MMP3 (0.67) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL27979824 | 0.91 | MMP3 (0.67) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL13825919 | 0.88 | MMP3 (0.71) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL20323049 | 0.86 | ESR1 (0.61) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL282856 | 0.85 | ALDH1A1 (0.50) | MMP3BCL2L1ESR1ESR2CA1 | |
| SCHEMBL29362903 | 0.85 | ALDH1A1 (0.50) | MMP3BCL2L1ESR1ESR2CA1 | |
| SCHEMBL5705575 | 0.85 | ESR1 (0.57) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL30692092 | 0.85 | ESR1 (0.57) | MMP3BCL2L1ESR1ESR2PDE4A | |
| SCHEMBL20936 | 0.85 | MAPT (0.48) | ESR1ESR2CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-8283002-B2 | Aminobenzene compositions and related devices and methods | PLEXTRONICS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283002-B2 | Aminobenzene compositions and related devices and methods | PLEXTRONICS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-20100292399-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. | 2010-11-18 | — | — | US | disclosed |
| US-20100292399-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. | 2010-11-18 | — | — | US | disclosed |
| WO-2010059646-A2 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | HLA-B, AAAS, SLCO2B1 | MMP3 4835/4885BCL2L1 3943/4885ESR1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.