Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.33 |
| ▸ | PRKDC | P78527 | 8/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970714 | 0.80 | CYP2A6 (0.37) | ABL1SRCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8975546 | 0.75 | ADK (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL3715031 | 0.74 | SRC (0.57) | ABL1SRCEGFRPRKCAPIK3CD | |
| SCHEMBL19257169 | 0.73 | PIK3CD (0.40) | ABL1SRCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13717957 | 0.72 | PIK3CD (0.58) | ABL1SRCEGFRPIK3CDPIK3CA | |
| SCHEMBL19414426 | 0.72 | PIK3CA (0.44) | PIK3CALRRK2MTORKDR | |
| SCHEMBL129539 | 0.70 | PIK3CD (0.59) | ABL1SRCEGFRPIK3CDPIK3CA | |
| SCHEMBL408618 | 0.70 | PIK3CD (0.55) | ABL1SRCEGFRPIK3CDPIK3CA | |
| SCHEMBL30387175 | 0.70 | PIK3CD (0.55) | ABL1SRCEGFRPIK3CDPIK3CA | |
| SCHEMBL887854 | 0.70 | ABL1 (0.44) | ABL1SRCEGFRPRKCAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151525-A9 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012151525-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2012-11-08 | — | — | WO | disclosed |