Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321507 | 0.84 | ADORA2A (0.39) | ADKCDK5CDK5R1MEN1KMT2A | |
| SCHEMBL8975540 | 0.75 | PIK3CD (0.60) | ADKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL13826002 | 0.75 | ABL1 (0.38) | RETCDK5MEN1KMT2ACDK2 | |
| SCHEMBL408618 | 0.74 | PIK3CD (0.55) | RETCDK5PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13717957 | 0.73 | PIK3CD (0.58) | ADKPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30124898 | 0.73 | STK4 (0.61) | ADKRETCDK5CLK1STK4 | |
| SCHEMBL17970714 | 0.72 | CYP2A6 (0.37) | MEN1KMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL5065122 | 0.72 | PIK3CD (0.57) | ADKRETCDK5PIK3CDPIK3CA | |
| SCHEMBL30387175 | 0.71 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL21048476 | 0.70 | PIK3CG (0.59) | STK4STK3ADORA2APIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |