Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.68 |
| ▸ | FAAH | O00519 | 5/20 | 0.67 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | SELP | P16109 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494183 | 1.00 | DNM1 (0.68) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL30632366 | 1.00 | DNM1 (0.68) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL5495532 | 1.00 | DNM1 (0.68) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL9001775 | 1.00 | DNM1 (0.68) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL5503356 | 1.00 | DNM1 (0.68) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL3117197 | 0.98 | DNM1 (0.65) | DNM1FAAHCASP2NAAAHSP90AA1 | |
| SCHEMBL3113406 | 0.92 | DNM1 (0.56) | DNM1FAAHCASP2NAAAHDAC3 | |
| SCHEMBL9203398 | 0.90 | EPHX2 (0.70) | FAAHEPHX2CNR1 | |
| SCHEMBL9203407 | 0.90 | EPHX2 (0.70) | FAAHEPHX2CNR1 | |
| SCHEMBL4343780 | 0.89 | HDAC3 (0.62) | DNM1FAAHCASP2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11726098-B2 | Method of diagnosing tuberculosis | UNIVERSITY OF PRETORIA (ZA) | 2023-08-15 | — | — | US | disclosed |
| US-20200150130-A1 | METHOD OF DIAGNOSING TUBERCULOSIS | UNIV PRETORIA (ZA) | 2020-05-14 | — | — | US | disclosed |
| US-10551391-B2 | Method of diagnosing tuberculosis | UNIVERSITY OF PRETORIA (ZA) | 2020-02-04 | — | — | US | disclosed |
| EP-2997371-B1 | A METHOD OF DIAGNOSING TUBERCULOSIS | UNIV PRETORIA (ZA) | 2018-11-07 | — | — | EP | disclosed |
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| EP-2705367-B1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIV (GB) | 2017-04-26 | — | — | EP | disclosed |
| EP-2705367-B1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIV (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20160169905-A1 | A METHOD OF DIAGNOSING TUBERCULOSIS | UNIVERSITY OF PRETORIA (ZA) | 2016-06-16 | — | — | US | disclosed |
| EP-2997371-A1 | A METHOD OF DIAGNOSING TUBERCULOSIS | University of Pretoria (ZA) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184768-A1 | A METHOD OF DIAGNOSING TUBERCULOSIS | UNIVERSITY OF PRETORIA (ZA) | 2014-11-20 | — | — | WO | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
| WO-2012153111-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | CA14, CD63, CA12 | DNM1 3396/4885FAAH 4244/4885CASP2 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.