Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470157 | 1.00 | PLA2G2A (0.44) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL15470167 | 0.96 | PLA2G2A (0.41) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL13827256 | 0.96 | PLA2G2A (0.41) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL18545053 | 0.93 | MMP12 (0.40) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL15470160 | 0.93 | PLA2G2A (0.39) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL13827253 | 0.93 | PLA2G2A (0.39) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL17278527 | 0.91 | PLA2G2A (0.37) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL15497941 | 0.90 | MMP12 (0.38) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL15470486 | 0.90 | PLA2G2A (0.37) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD | |
| SCHEMBL15470376 | 0.90 | PLA2G2A (0.37) | PLA2G2APLA2G4ASMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705552-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-20140061548-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent CmbH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20140061548-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent CmbH (DE) | 2014-03-06 | — | — | US | disclosed |
| WO-2012150001-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-11-08 | — | — | WO | disclosed |