Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827328 | 0.93 | SLC6A9 (0.61) | SLC6A9SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL13827790 | 0.91 | SLC6A9 (0.42) | SLC6A9SLC22A1PRCPKDM1AMAPT | |
| SCHEMBL13827336 | 0.91 | SLC6A9 (0.42) | SLC6A9SLC22A1PRCPKDM1AMAPT | |
| SCHEMBL13738182 | 0.91 | SLC6A9 (0.48) | SLC6A9SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL17675764 | 0.89 | SLC6A9 (0.42) | SLC6A9SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL15187757 | 0.87 | SLC6A9 (0.50) | SLC6A9SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL13827504 | 0.86 | SLC6A9 (0.41) | SLC6A9MAPTKDM4EMEN1USP2 | |
| SCHEMBL17675750 | 0.85 | SLC22A1 (0.44) | SLC6A9SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL13736420 | 0.84 | SLC22A1 (0.50) | SLC22A1PRCPADRB2KDM1AMAPT | |
| SCHEMBL14152143 | 0.84 | SLC22A1 (0.52) | SLC22A1PRCPADRB2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2012152915-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-11-15 | — | — | WO | disclosed |