Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675755 | 0.94 | SLC6A9 (0.50) | SLC6A9KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13738306 | 0.91 | SLC6A9 (0.39) | SLC6A9MEN1KMT2AALKBH5GAA | |
| SCHEMBL13827790 | 0.90 | SLC6A9 (0.42) | SLC6A9KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13827331 | 0.89 | SLC6A9 (0.52) | SLC6A9KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13827336 | 0.84 | SLC6A9 (0.42) | SLC6A9KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17675749 | 0.84 | SLC6A9 (0.46) | SLC6A9 | |
| SCHEMBL13827788 | 0.83 | SLC6A9 (0.51) | SLC6A9KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17675754 | 0.83 | POLB (0.40) | SLC6A9MAPTKMT2AHTR6GHSR | |
| SCHEMBL13827328 | 0.82 | SLC6A9 (0.61) | SLC6A9SLC22A1PRCPGHSRADRB2 | |
| SCHEMBL17675751 | 0.82 | SLC6A9 (0.56) | SLC6A9MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |