Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827329 | 0.92 | SLC6A9 (0.67) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL17675751 | 0.92 | SLC6A9 (0.56) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL13827337 | 0.92 | SLC6A9 (0.57) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL13827334 | 0.83 | SLC6A9 (0.51) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL13738539 | 0.81 | SLC6A9 (0.64) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL13827790 | 0.81 | SLC6A9 (0.42) | SLC6A9KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL7896728 | 0.80 | SLC6A9 (0.70) | SLC6A9KMT2ALMNAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL3093002 | 0.80 | SLC6A9 (0.69) | SLC6A9KMT2ALMNAGAAMEN1 | |
| SCHEMBL13827501 | 0.79 | SLC6A9 (0.70) | SLC6A9KMT2AKCNH2 | |
| SCHEMBL13827231 | 0.79 | SLC6A9 (0.59) | SLC6A9KMT2ALMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2012152915-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-11-15 | — | — | WO | disclosed |