Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827337 | 0.92 | SLC6A9 (0.57) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL13827792 | 0.92 | SLC6A9 (0.57) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL17675751 | 0.91 | SLC6A9 (0.56) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL13738539 | 0.89 | SLC6A9 (0.64) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL13827334 | 0.87 | SLC6A9 (0.51) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL13737074 | 0.86 | SLC6A9 (0.69) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL17675708 | 0.84 | MEN1 (0.57) | SLC6A9LMNAKCNH2KMT2AMEN1 | |
| SCHEMBL13827486 | 0.83 | SLC6A9 (0.71) | SLC6A9LMNAKCNH2KMT2AGAA | |
| SCHEMBL13827404 | 0.83 | SLC6A9 (0.47) | SLC6A9KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL17675709 | 0.83 | SLC6A9 (0.47) | SLC6A9KCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| WO-2012152915-A1 | BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-11-15 | — | — | WO | disclosed |