Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386672 | 0.87 | KMT2A (0.43) | LMNAPOLBSMN1; SMN2L3MBTL1KCNK3 | |
| SCHEMBL1385564 | 0.86 | CASR (0.40) | LMNARXFP1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL1383781 | 0.86 | EPHX2 (0.45) | LMNAPOLBSMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL1386210 | 0.84 | EPHX2 (0.42) | LMNAPOLBSMN1; SMN2L3MBTL1KCNK3 | |
| SCHEMBL1386145 | 0.84 | CASR (0.39) | LMNARXFP1POLBCASR | |
| SCHEMBL1384916 | 0.83 | EPHX2 (0.45) | LMNAPOLBSMN1; SMN2TSHRKCNK3 | |
| SCHEMBL1385431 | 0.83 | MAPT (0.42) | LMNASMN1; SMN2HPGDKCNK3KCNK9 | |
| SCHEMBL1384630 | 0.83 | SMN1; SMN2 (0.42) | LMNAPOLBSMN1; SMN2L3MBTL1KCNK3 | |
| SCHEMBL1386047 | 0.83 | CASR (0.44) | LMNAPOLBKCNK3KCNK9CASR | |
| SCHEMBL1383762 | 0.82 | KCNK3 (0.42) | LMNARXFP1POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |