Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386145 | 0.90 | CASR (0.39) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1386672 | 0.90 | KMT2A (0.43) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1383781 | 0.89 | EPHX2 (0.45) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1386210 | 0.87 | EPHX2 (0.42) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1384916 | 0.86 | EPHX2 (0.45) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL1385431 | 0.86 | MAPT (0.42) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1384630 | 0.86 | SMN1; SMN2 (0.42) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1386047 | 0.86 | CASR (0.44) | CASRKMT2ALMNAPOLBKDM4E | |
| SCHEMBL1382882 | 0.86 | LMNA (0.44) | CASRLMNAPOLBRXFP1SMN1; SMN2 | |
| SCHEMBL1383762 | 0.85 | KCNK3 (0.42) | CASRMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |