Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386672 | 0.89 | KMT2A (0.43) | CASRKCNK3MCHR1POLBKMT2A | |
| SCHEMBL1386105 | 0.88 | MEN1 (0.47) | CASRKCNK3KCNK9POLBKMT2A | |
| SCHEMBL1383781 | 0.87 | EPHX2 (0.45) | CASRKCNK3KCNK9ABL1BCR | |
| SCHEMBL5711059 | 0.87 | KCNK3 (0.45) | KCNK3KCNK9ABL1EGFRPDGFRB | |
| SCHEMBL1386210 | 0.86 | EPHX2 (0.42) | CASRKCNK3ABL1PDGFRBBCR | |
| SCHEMBL1385564 | 0.86 | CASR (0.40) | CASRPOLBKMT2AKDM4ELMNA | |
| SCHEMBL1385431 | 0.85 | MAPT (0.42) | CASRKCNK3KCNK9ABL1PDGFRB | |
| SCHEMBL1384630 | 0.85 | SMN1; SMN2 (0.42) | CASRKCNK3KCNK9POLBKMT2A | |
| SCHEMBL1384916 | 0.85 | EPHX2 (0.45) | KCNK3ABL1PDGFRBBCRPDGFRA | |
| SCHEMBL1386145 | 0.84 | CASR (0.39) | CASRPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |