Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CCKBR | P32239 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384714 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1CCKBRKMT2AMEN1 | |
| SCHEMBL1889700 | 0.90 | CCKBR (0.58) | CCKBRCCKAR | |
| SCHEMBL1884936 | 0.90 | CCKBR (0.59) | KDM4ECCKBRCCKAR | |
| SCHEMBL4688617 | 0.90 | CCKBR (0.55) | KDM4EALDH1A1CCKBRCCKARLMNA | |
| SCHEMBL3899664 | 0.86 | L3MBTL1 (0.60) | KDM4ECCKBRKMT2AMEN1CCKAR | |
| SCHEMBL1382888 | 0.84 | CCKBR (0.54) | KDM4EALDH1A1CCKBRCCKARTSHR | |
| SCHEMBL1896151 | 0.82 | CCKBR (0.58) | CCKBRCCKAR | |
| SCHEMBL1889522 | 0.81 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL1385714 | 0.81 | CCKBR (0.51) | KDM4EALDH1A1CCKBRKMT2AMEN1 | |
| SCHEMBL1382499 | 0.80 | CCKBR (0.50) | KDM4EALDH1A1CCKBRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4818110-B2 | — | — | 2011-11-16 | — | — | JP | claimed |