SCHEMBL13829463

SCHEMBL13829463

Cc1ccc2c(ccc3cc(N(c4ccc5ccccc5c4)c4cccc5ccccc45)ccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 8/20 0.44
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
HPGD P15428 3/20 0.41
MAOA P21397 2/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1B1 Q16678 2/20 0.38
HIF1A Q16665 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
HPRT1 P00492 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
CYP1A1 P04798 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14242300 0.96 CYP2A6 (0.53) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL13367588 0.93 MAOA (0.43) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL17702100 0.91 CYP1A2 (0.42) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL13367607 0.91 CYP2A6 (0.50) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL14070177 0.91 ALDH1A1 (0.45) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL13367566 0.90 CYP2A6 (0.46) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL16627123 0.90 HTT (0.46) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL18134984 0.90 HTT (0.46) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL18134990 0.88 HTT (0.44) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL18134986 0.88 HTT (0.44) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012148127-A2 COMPOUND, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2012-11-01 WO disclosed