Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559053 | 0.91 | ALDH1A1 (0.69) | ALDH1A1MAPK1LMNAHTTKMT2A | |
| SCHEMBL18559319 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MAPK1LMNAHTTPOLB | |
| SCHEMBL15986083 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MAPK1LMNAHTTKMT2A | |
| SCHEMBL18556524 | 0.89 | ALDH1A1 (0.65) | ALDH1A1MAPK1LMNAHTTPOLB | |
| SCHEMBL18559057 | 0.89 | ALDH1A1 (1.00) | ALDH1A1MAPK1LMNAHTTPOLB | |
| SCHEMBL4211839 | 0.89 | ALDH1A1 (0.75) | ALDH1A1MAPK1POLBTDP1USP2 | |
| SCHEMBL18559114 | 0.89 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBTDP1KMT2A | |
| SCHEMBL13737637 | 0.86 | KMT2A (0.75) | ALDH1A1MAPK1LMNAHTTKMT2A | |
| SCHEMBL18556548 | 0.84 | MAPK1 (0.70) | ALDH1A1MAPK1LMNAHTTPOLB | |
| SCHEMBL4215761 | 0.84 | LMNA (0.74) | ALDH1A1MAPK1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |
| WO-2012154403-A9 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |