SCHEMBL13832157

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13832308	0.89	LMNA (0.55)	TSHRMAPTKMT2AGAAALDH1A1
	SCHEMBL13831121	0.89	TSHR (0.45)	TSHRMAPTPOLBKMT2AGAA
	SCHEMBL13831227	0.88	GAA (0.55)	TSHRMAPTPOLBKMT2AGAA
	SCHEMBL13832106	0.86	GAA (0.45)	TSHRMAPTKMT2AGAAHSD17B10
	SCHEMBL13831759	0.85	NPSR1 (0.45)	TSHRMAPTKMT2AGAAHSD17B10
	SCHEMBL13831696	0.85	GAA (0.45)	TSHRMAPTKMT2AGAATP53
	SCHEMBL13831697	0.83	GAA (0.45)	TSHRMAPTPOLBKMT2AGAA
	SCHEMBL13832248	0.83	GAA (0.43)	TSHRMAPTPOLBGAANPC1
	SCHEMBL13832143	0.83	TSHR (0.46)	TSHRMAPTPOLBKMT2AGAA
	SCHEMBL13831266	0.83	GAA (0.44)	TSHRGAANPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.