SCHEMBL14010642

SCHEMBL14010642

Cc1ccccc1N(c1ccc(-c2ccc(N(c3ccccc3C)c3ccc4c5c(cccc35)-c3ccccc3-4)cc2)cc1)c1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
PABPC1 P11940 2/20 0.41
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
USP2 O75604 4/20 0.39
ALDH1A1 P00352 4/20 0.39
CASP1 P29466 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CRHBP P24387 2/20 0.39
CRHR2 Q13324 2/20 0.39
CASP7 P55210 2/20 0.39
HBB P68871 2/20 0.39
GAA P10253 1/20 0.39
BRCA1 P38398 1/20 0.39
KEAP1 Q14145 2/20 0.37
NFE2L2 Q16236 2/20 0.37
POLB P06746 1/20 0.35
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14010647 0.89 CRHBP (0.44) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL14010646 0.85 ALDH1A1 (0.41) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL14010644 0.85 KDM4E (0.40) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL13832166 0.84 KDM4E (0.43) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL14010649 0.84 CRHBP (0.38) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL23546630 0.83 CRHBP (0.42) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL14491574 0.83 CRHBP (0.42) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL5002787 0.83 CRHBP (0.42) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL23546674 0.82 CRHBP (0.41) MAPTPABPC1KDM4ESMN1; SMN2MEN1
SCHEMBL12566482 0.82 CRHBP (0.41) MAPTPABPC1KDM4ESMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080278065-A1 Organic Electroluminescent Element and Display Apparatus SONY CORPORATION (JP) 2008-11-13 US disclosed
US-20080278065-A1 Organic Electroluminescent Element and Display Apparatus SONY CORPORATION (JP) 2008-11-13 US disclosed
US-20070149815-A1 Organic light-emitting material and method for producing an organic material SONY CORPORATION (JP) 2007-06-28 US disclosed
US-20070149815-A1 Organic light-emitting material and method for producing an organic material SONY CORPORATION (JP) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149815-A1 Organic light-emitting material and method for producing an organic material CRY1, CRY2, IK MAPT 1013/4885PABPC1 1812/4885KDM4E 2873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.