Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831123 | 0.93 | ACACB (0.33) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL13832382 | 0.93 | ACACB (0.33) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| Hydrochloric Acid SCHEMBL13739442 | 0.92 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| Hydrochloric Acid SCHEMBL13738425 | 0.92 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| Hydrochloric Acid SCHEMBL13738426 | 0.92 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| Hydrochloric Acid SCHEMBL13739441 | 0.92 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL18100459 | 0.91 | PIN1 (0.32) | P2RY6 | |
| SCHEMBL19102808 | 0.91 | PIN1 (0.32) | P2RY6 | |
| SCHEMBL19102805 | 0.91 | PIN1 (0.32) | P2RY6 | |
| SCHEMBL17453189 | 0.91 | PIN1 (0.32) | P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154204-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | ACHAOGEN, INC. (US) | 2012-11-15 | — | — | WO | disclosed |