Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102808 | 1.00 | PIN1 (0.32) | PIN1TAS1R3TAS1R1HPGDSPLAU | |
| SCHEMBL19102805 | 1.00 | PIN1 (0.32) | PIN1TAS1R3TAS1R1HPGDSPLAU | |
| SCHEMBL17451860 | 1.00 | PIN1 (0.32) | PIN1TAS1R3TAS1R1HPGDSPLAU | |
| SCHEMBL18100459 | 1.00 | PIN1 (0.32) | PIN1TAS1R3TAS1R1HPGDSPLAU | |
| SCHEMBL17435817 | 1.00 | PIN1 (0.32) | PIN1TAS1R3TAS1R1HPGDSPLAU | |
| SCHEMBL19756326 | 0.94 | PIN1 (0.32) | PIN1PLAUPLAT | |
| SCHEMBL13832175 | 0.91 | ACACB (0.34) | P2RY6 | |
| SCHEMBL17435716 | 0.89 | ADAM17 (0.35) | PIN1 | |
| SCHEMBL17435718 | 0.89 | ADAM17 (0.35) | PIN1 | |
| SCHEMBL19102697 | 0.89 | ADAM17 (0.35) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
| US-9403758-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | PIN1 1074/4885TAS1R3 4049/4885TAS1R1 3410/4885 |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | PIN1 1074/4885TAS1R3 4049/4885TAS1R1 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.