Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860445 | 1.00 | — | — | |
| SCHEMBL8860654 | 1.00 | DRD2 (0.47) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL17996818 | 1.00 | DRD2 (0.47) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL3970694 | 1.00 | DRD2 (0.47) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL636364 | 1.00 | DRD2 (0.47) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL24688086 | 0.92 | MEN1 (0.50) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL17996819 | 0.92 | MEN1 (0.50) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL4650626 | 0.92 | DRD2 (0.44) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL14906559 | 0.92 | PIK3CD (0.56) | DRD2DRD3PIK3CDMEN1KMT2A | |
| SCHEMBL17968369 | 0.92 | MEN1 (0.50) | DRD2DRD3PIK3CDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246949-B2 | Imaging contrast agents and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-02-15 | — | — | US | disclosed |
| US-10960088-B2 | Macrocycles, cobalt and iron complexes of same, and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-03-30 | — | — | US | disclosed |
| US-20160228581-A1 | MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2016-08-11 | — | — | US | disclosed |
| US-20160228581-A1 | MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2016-08-11 | — | — | US | disclosed |
| WO-2015038943-A1 | MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK UNIVERSITY AT BUFFALO (US) | 2015-03-19 | — | — | WO | disclosed |
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-07-10 | — | — | US | disclosed |
| WO-2012155076-A2 | IMAGING CONTRAST AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193344-A1 | IMAGING CONTRAST AGENTS AND USES THEREOF | SLC40A1, SLC39A14, SLC39A3 | DRD2 2287/4885DRD3 2637/4885PIK3CD 4319/4885 |
| US-20160228581-A1 | MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME | ABCB7, FECH, CYC1 | DRD2 4039/4885DRD3 3343/4885PIK3CD 4454/4885 |
| US-11246949-B2 | Imaging contrast agents and uses thereof | SLC40A1, SLC39A14, SLC39A3 | DRD2 2287/4885DRD3 2637/4885PIK3CD 4319/4885 |
| US-10960088-B2 | Macrocycles, cobalt and iron complexes of same, and methods of making and using same | ABCB7, FECH, CYC1 | DRD2 4039/4885DRD3 3343/4885PIK3CD 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.