Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.63 |
| ▸ | HINT1 | P49773 | 6/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 6/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16113889 | 1.00 | AHCY (0.64) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL16113892 | 1.00 | AHCY (0.64) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL17439986 | 1.00 | AHCY (0.64) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL17469466 | 1.00 | AHCY (0.64) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL17198347 | 0.89 | NT5E (0.55) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL16787413 | 0.88 | AHCY (0.59) | AHCYNT5EHINT1TGM2HPGD | |
| SCHEMBL26622869 | 0.88 | HINT1 (0.56) | AHCYNT5EHINT1TGM2GSK3A | |
| SCHEMBL19130245 | 0.88 | HINT1 (0.56) | AHCYNT5EHINT1TGM2GSK3A | |
| Guanosine SCHEMBL17441728 | 0.87 | HPGD (0.70) | NT5EHINT1TGM2GSK3ARPS6KA3 | |
| SCHEMBL25775138 | 0.86 | NT5E (0.53) | AHCYNT5EHINT1TGM2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707487-B1 | RIBOSWITCHES | UNIV MANCHESTER (GB) | 2017-10-04 | — | — | EP | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| WO-2012153142-A2 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2012-11-15 | — | — | WO | disclosed |