SCHEMBL13835010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19791447	0.94	IDO1 (0.39)	IDO1RETSUCNR1HCAR2KDR
	SCHEMBL12440283	0.93	IDO1 (0.38)	IDO1RETSUCNR1HCAR2HRH3
	SCHEMBL19791688	0.90	CYP51A1 (0.36)	RETSUCNR1HCAR2CYP11B1CYP11B2
	SCHEMBL12440011	0.87	IDO1 (0.44)	IDO1HCAR2KDRWNT1
	SCHEMBL12440325	0.83	PDGFRB (0.40)	IDO1SUCNR1CYP11B1CYP11B2ACP1
	SCHEMBL2321937	0.83	MAPK1 (0.40)	IDO1CYP11B1CYP11B2ACP1
	SCHEMBL12440280	0.83	MCHR1 (0.40)	RETSUCNR1CDK1KDRHRH3
	SCHEMBL19791573	0.82	ACP1 (0.41)	RETCDK1HRH3ACP1WNT1
	SCHEMBL12440047	0.82	TGFBR1 (0.46)	IDO1KDR
	SCHEMBL19791445	0.82	MCHR1 (0.42)	RETSUCNR1KDRHRH3ACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.