SCHEMBL12440280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19791573	0.99	ACP1 (0.41)	MCHR1RETACP1DRD4DRD2
	SCHEMBL19791445	0.95	MCHR1 (0.42)	MCHR1RETACP1DRD4DRD2
	SCHEMBL12440257	0.93	TNIK (0.42)	DRD4DRD2HTR2ASCN2ASCN10A
	SCHEMBL13834517	0.92	SLC6A3 (0.38)	RETACP1DRD4DRD2HTR2A
	SCHEMBL19791749	0.91	RET (0.41)	RETDRD4DRD2HRH3LTA4H
	SCHEMBL12441219	0.88	ACHE (0.44)	MCHR1HTR2ALTA4HACHEKDR
	SCHEMBL19791572	0.88	KDR (0.39)	MCHR1SCN2ASCN10AKDR
	SCHEMBL2320748	0.85	MET (0.40)	MCHR1ACP1DRD4KDR
	SCHEMBL12440260	0.84	WNT1 (0.46)	HRH3LTA4HAVPR1B
	SCHEMBL13835010	0.83	IDO1 (0.38)	RETACP1HRH3SUCNR1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.