Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.57 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835497 | 1.00 | ADORA3 (0.64) | ADORA3ADORA2AADORA2BDNMT1DNMT3B | |
| SCHEMBL13835563 | 0.89 | ADORA2A (0.72) | ADORA2AADORA2B | |
| SCHEMBL13835562 | 0.89 | ADORA2A (0.72) | ADORA2AADORA2B | |
| SCHEMBL13966950 | 0.88 | DOT1L (0.62) | ADORA3ADORA2AADORA2B | |
| SCHEMBL13835718 | 0.88 | ADORA2A (0.61) | ADORA2AADORA2B | |
| SCHEMBL13835721 | 0.88 | ADORA2A (0.61) | ADORA2AADORA2B | |
| SCHEMBL5351501 | 0.85 | ADORA2A (0.77) | ADORA3ADORA2AADORA2B | |
| SCHEMBL5351524 | 0.85 | ADORA2A (0.77) | ADORA3ADORA2AADORA2B | |
| SCHEMBL13978090 | 0.84 | ADORA3 (0.53) | ADORA3ADORA2AADORA2B | |
| SCHEMBL13835577 | 0.82 | ADORA2A (0.79) | ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED | 2015-11-12 | — | — | US | disclosed |
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2015-11-12 | — | — | US | disclosed |
| US-9120820-B2 | Fluorescent molecular probes for use in assays that measure test compound competitive binding with SAM-utilizing proteins | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2015-09-01 | — | — | US | disclosed |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012159072-A2 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | ADORA3 1318/4885ADORA2A 1411/4885ADORA2B 4114/4885 |
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | ADORA3 1318/4885ADORA2A 1411/4885ADORA2B 4114/4885 |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | ADORA3 1318/4885ADORA2A 1411/4885ADORA2B 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.