Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18477590 | 0.95 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL14498156 | 0.90 | TSHR (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13871148 | 0.88 | TSHR (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10171087 | 0.86 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13871139 | 0.86 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL31288177 | 0.83 | CA1 (0.47) | CA1CA2THRB | |
| SCHEMBL9859595 | 0.83 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10823303 | 0.83 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28134720 | 0.82 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL14550803 | 0.80 | ALDH1A1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120296029-A1 | FLUORINE-CONTAINING MULTIFUNCTIONAL MICROSPHERES AND USES THEREOF | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-11-22 | — | — | US | disclosed |