SCHEMBL138381

SCHEMBL138381

COC(=O)COc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
POLB P06746 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.40
ATAD2 Q6PL18 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1624884 0.94 LMNA (0.42) LMNAPOLBKMT2AMEN1CYP1A2
SCHEMBL6130762 0.84 KMT2A (0.44) LMNAPOLBKMT2AMEN1GAA
SCHEMBL103605 0.81 GAA (0.44) LMNAPOLBCYP1A2GAAATAD2
Acetic Acid Methyl Ester SCHEMBL28329738 0.81 POLB (0.52) LMNAPOLBKMT2AGAAATAD2
SCHEMBL6647291 0.77 POLB (0.50) LMNAPOLBGAAATAD2TP53
Acetic Acid SCHEMBL27871291 0.77 POLB (0.51) LMNAPOLBCYP1A2GAAATAD2
Thymine SCHEMBL6686289 0.76 ATAD2 (0.58) LMNAPOLBGAAATAD2TP53
SCHEMBL104485 0.75 KMT2A (0.51) LMNAKMT2AGAAATAD2MAPT
SCHEMBL28628364 0.74 LMNA (0.39) LMNAKMT2AGAAATAD2
SCHEMBL1162321 0.74 POLB (0.46) LMNAPOLBKMT2ACYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4858 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-12552858-B2 Methods and compositions for delivering mRNA coded antibodies TRANSLATE BIO, INC. (US) 2026-02-17 US claimed
EP-4659246-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES Atlas Data Storage, Inc. (US) 2025-12-10 EP claimed
US-20250368986-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES ATLAS DATA STORAGE INC (US) 2025-12-04 US claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 US claimed
WO-2025137576-A1 MULTIPLE SPECIFIC ANTIBODIES TARGETING CD19, CD20, AND/OR CD47 NUTCRACKER THERAPEUTICS, INC. (US) 2025-06-26 WO claimed
EP-4504945-A2 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER The Board of Regents of the University of Oklahoma (US) 2025-02-12 EP claimed
US-12146139-B2 Oligonucleotide interference treatments of prostate cancer THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2024-11-19 US claimed
US-20130195867-A1 RNA-CODED ANTIBODY CUREVAC GMBH (DE) 2013-08-01 US claimed
WO-2012138530-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-10-11 WO claimed
US-7807356-B2 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. (US) 2010-10-05 US claimed
US-20100189729-A1 RNA-CODED ANTIBODY CURVAC GMBH (DE) 2010-07-29 US claimed
EP-2101823-A2 RNA-CODED ANTIBODY Curevac GmbH (DE) 2009-09-23 EP claimed
US-7524942-B2 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. (US) 2009-04-28 US claimed
WO-2008083949-A2 RNA-CODED ANTIBODY CUREVAC GMBH (DE) 2008-07-17 WO claimed
US-20080124708-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2008-05-29 US claimed
US-20070212697-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2007-09-13 US claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed