Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLRK1 | P26718 | 2/20 | 0.37 |
| ▸ | MICA | Q29983 | 2/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727744 | 0.75 | CSNK1D (0.41) | TRPV1WNT3AABCB1ABCC1NTRK1 | |
| SCHEMBL13838516 | 0.69 | ABL1 (0.49) | F10ABCB1ABCC1BRAFABL1 | |
| SCHEMBL13730219 | 0.68 | ABL1 (0.43) | ABCB1ABCC1ABL1 | |
| SCHEMBL19228843 | 0.67 | ABL1 (0.42) | F10ABCB1ABCC1ABL1KDR | |
| SCHEMBL13838334 | 0.67 | F10 (0.46) | F10ABCB1ABCC1BRAFABL1 | |
| SCHEMBL18996622 | 0.66 | RAB9A (0.47) | TRPV1BRAF | |
| SCHEMBL19228842 | 0.66 | ABCB1 (0.39) | F10ABCB1ABCC1 | |
| SCHEMBL16363154 | 0.65 | S1PR1 (0.50) | F10TRPV1GPBAR1BRAF | |
| SCHEMBL13838607 | 0.65 | ABL1 (0.41) | ABCB1ABL1 | |
| SCHEMBL13838456 | 0.64 | NPC1 (0.47) | ABCB1ABCC1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |