Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 3/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 12/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838459 | 0.90 | ABCB1 (0.36) | MAP4K1ABL1 | |
| SCHEMBL18670930 | 0.83 | RAB9A (0.43) | IL2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13727611 | 0.80 | IL2 (0.41) | IL2ABL1 | |
| SCHEMBL13838345 | 0.79 | KDM1A (0.40) | IL2MAP4K1ABL1 | |
| SCHEMBL15803768 | 0.79 | IL2 (0.43) | IL2MAP4K1ABL1 | |
| SCHEMBL18671426 | 0.77 | IL2 (0.39) | IL2MAP4K1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15793257 | 0.76 | RAB9A (0.39) | IL2 | |
| SCHEMBL21316350 | 0.76 | IL2 (0.43) | IL2 | |
| SCHEMBL13838404 | 0.73 | DYRK1A (0.47) | IL2MAP4K1 | |
| SCHEMBL13728380 | 0.72 | IL2 (0.40) | IL2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |