Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 5/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13838527 | 0.90 | IL2 (0.36) | ABL1MAP4K1 | |
| SCHEMBL13838609 | 0.80 | — | — | |
| SCHEMBL15793607 | 0.76 | RAB9A (0.39) | ABCB1ABCC1NPC1TP53GAA | |
| SCHEMBL13728018 | 0.74 | DYRK1A (0.49) | MAP4K1 | |
| SCHEMBL13838352 | 0.71 | WNT1 (0.43) | ABCB1ABCC1ABL1MAP4K1 | |
| SCHEMBL18670930 | 0.71 | RAB9A (0.43) | STIM1ORAI1NPC1MITFTP53 | |
| SCHEMBL13838416 | 0.71 | PORCN (0.44) | ABCB1ABCC1PORCNNPC1RAB9A | |
| SCHEMBL13728434 | 0.69 | ABL1 (0.46) | ABCB1ABCC1ABL1 | |
| SCHEMBL13727611 | 0.69 | IL2 (0.41) | ABL1NPC1RAB9A | |
| SCHEMBL13838462 | 0.68 | ABL1 (0.44) | ABCB1ABCC1ABL1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |