Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839657 | 0.86 | ALDH1A1 (0.46) | ALDH1A1POLBHTTNPSR1LMNA | |
| SCHEMBL13839655 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBHTTKCNA5NPSR1 | |
| SCHEMBL13839650 | 0.76 | ALDH1A1 (0.40) | ALDH1A1POLBHTTHSD17B10NPSR1 | |
| SCHEMBL13839653 | 0.75 | KMT2A (0.47) | ALDH1A1POLBHTTSMN1; SMN2MAPK1 | |
| SCHEMBL13839642 | 0.75 | POLB (0.44) | ALDH1A1POLBHTTSMN1; SMN2NPSR1 | |
| SCHEMBL1449085 | 0.74 | LMNA (0.54) | ALDH1A1HTTSMN1; SMN2LMNACYP11B1 | |
| SCHEMBL13839491 | 0.73 | ALDH1A1 (0.47) | ALDH1A1POLBHTTSMN1; SMN2MAPK1 | |
| SCHEMBL13839643 | 0.73 | HTT (0.43) | ALDH1A1POLBHTTSMN1; SMN2MAPK1 | |
| SCHEMBL14424039 | 0.72 | ALDH1A1 (0.42) | ALDH1A1POLBHTTMAPK1HSD17B10 | |
| SCHEMBL13841234 | 0.72 | SRC (0.44) | ALDH1A1POLBHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |