Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.56 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | QDPR | P09417 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31527834 | 0.84 | ALOX15 (0.53) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL27183326 | 0.84 | ALOX15 (0.53) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL30873037 | 0.84 | ALOX15 (0.53) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL17938800 | 0.84 | ESR1 (0.78) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL30912699 | 0.84 | ESR1 (0.78) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL30217572 | 0.84 | ESR1 (0.78) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL7531682 | 0.83 | ESR2 (0.71) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL29149123 | 0.81 | ALOX15 (0.47) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL19560169 | 0.79 | ALOX15B (0.55) | ALOX15ALOX12ALOX15BESR1ESR2 | |
| SCHEMBL577507 | 0.79 | NISCH (0.54) | ALOX15ALOX12ALOX15BESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531646-B2 | β-D-ribosidase activity indicators with a chromogenic substrate | BURTON MICHAEL | 2009-05-12 | — | — | US | disclosed |
| US-7531646-B2 | β-D-ribosidase activity indicators with a chromogenic substrate | BURTON MICHAEL | 2009-05-12 | — | — | US | disclosed |
| EP-1438423-B1 | ENZYME ACTIVITY INDICATORS | BURTON MICHAEL (GB) | 2007-12-12 | — | — | EP | disclosed |