Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | RORC | P51449 | 5/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113681 | 0.89 | KDM4E (0.66) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL10113401 | 0.89 | KDM4E (0.66) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL15899235 | 0.85 | KDM4E (0.80) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL13840447 | 0.83 | MAPT (0.66) | KDM4EMAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL15899344 | 0.81 | KDM4E (0.78) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL4725254 | 0.81 | MAPT (0.85) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL15899195 | 0.81 | RORC (1.00) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL1594241 | 0.81 | KDM4E (0.76) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL4728399 | 0.80 | KDM4E (0.83) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL4728393 | 0.80 | KDM4E (0.83) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534892-B2 | Sulfonamide compound | SHIONOGI & CO., LTD. (JP) | 2009-05-19 | — | — | US | disclosed |
| US-7534892-B2 | Sulfonamide compound | SHIONOGI & CO., LTD. (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | SHIONOGI & CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | SHIONOGI & CO., LTD. (JP) | 2007-12-13 | — | — | US | disclosed |
| EP-1760073-A1 | SULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287710-A1 | Piperidinediyl-containing sulfonamide; NPY Y5 receptor antagonist activity; antiobesity agent or anorectic agent | NPY5R, NPY1R, NPY2R | KDM4E 704/4885MAPT 4654/4885MEN1 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.