Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.83 |
| ▸ | MAPT | P10636 | 7/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.83 |
| ▸ | RORC | P51449 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728399 | 1.00 | KDM4E (0.83) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL4727374 | 0.89 | KDM4E (0.78) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL4725254 | 0.89 | MAPT (0.85) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL4728967 | 0.88 | KDM4E (0.64) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL1593514 | 0.88 | KDM4E (0.83) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL4728971 | 0.88 | KDM4E (0.64) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL14199692 | 0.87 | MAPT (0.82) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL15899270 | 0.86 | RORC (1.00) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL1594133 | 0.85 | KDM4E (0.80) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL15899235 | 0.85 | KDM4E (0.80) | KDM4EMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |