Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | CASR | P41180 | 5/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913906 | 1.00 | ADRB2 (0.47) | ADRB2ADRB1CASRMRGPRX4ALDH1A1 | |
| SCHEMBL13840627 | 0.92 | ADRB2 (0.39) | ADRB2ADRB1CASR | |
| SCHEMBL3912622 | 0.91 | LOXL2 (0.40) | ADRB2ADRB1MRGPRX4ALDH1A1FOLH1 | |
| SCHEMBL13840616 | 0.91 | LOXL2 (0.40) | ADRB2ADRB1MRGPRX4ALDH1A1FOLH1 | |
| SCHEMBL13840623 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1CASR | |
| SCHEMBL3914619 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1CASR | |
| SCHEMBL13840633 | 0.86 | ADRB2 (0.40) | ADRB2ADRB1CASR | |
| SCHEMBL4388444 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1CASRNFKB1 | |
| SCHEMBL4388443 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1CASRNFKB1 | |
| SCHEMBL13840618 | 0.84 | PARP1 (0.42) | ALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |