SCHEMBL13840643

SCHEMBL13840643

CCCCCCCC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.64
PTGS1 P23219 4/20 0.64
ALOX5 P09917 2/20 0.64
HSD17B3 P37058 6/20 0.54
F2R P25116 2/20 0.53
FFAR1 O14842 1/20 0.53
PLA2G2A P14555 1/20 0.53
PLA2G5 P39877 1/20 0.53
LMNA P02545 1/20 0.51
RECQL P46063 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783447 1.00 PTGS2 (0.64) PTGS2PTGS1ALOX5HSD17B3F2R
SCHEMBL9359469 0.98 PTGS2 (0.66) PTGS2PTGS1ALOX5HSD17B3F2R
SCHEMBL11615584 0.93 PTGS2 (0.68) PTGS2PTGS1ALOX5HSD17B3F2R
SCHEMBL25760152 0.87 PTGS2 (0.64) PTGS2PTGS1ALOX5F2RLMNA
SCHEMBL7352493 0.87 PTGS2 (0.64) PTGS2PTGS1ALOX5F2RLMNA
SCHEMBL23293040 0.87 PTGS2 (0.64) PTGS2PTGS1ALOX5F2RLMNA
SCHEMBL7356996 0.87 PTGS2 (0.64) PTGS2PTGS1ALOX5F2RLMNA
SCHEMBL7348363 0.87 PTGS2 (0.64) PTGS2PTGS1ALOX5F2RLMNA
SCHEMBL11618543 0.86 PTGS2 (0.62) PTGS2PTGS1ALOX5HSD17B3F2R
SCHEMBL27411148 0.86 PTGS2 (0.62) PTGS2PTGS1ALOX5F2RFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed