Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348363 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL7352493 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL1926015 | 0.88 | ALOX5 (0.60) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL25760152 | 0.87 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL27783447 | 0.87 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL23293040 | 0.87 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL13840643 | 0.87 | PTGS2 (0.64) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL27392264 | 0.86 | PTGS2 (0.62) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL27411148 | 0.86 | PTGS2 (0.62) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL9359469 | 0.85 | PTGS2 (0.66) | PTGS2PTGS1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675883-A1 | PIPERIDINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014786-A1 | PIPERIDINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |