Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709099 | 0.67 | QPCT (0.44) | NQO2MTNR1AMTNR1B | |
| SCHEMBL3709096 | 0.67 | QPCT (0.44) | NQO2MTNR1AMTNR1B | |
| SCHEMBL15463276 | 0.63 | HDAC1 (0.37) | MTNR1AMTNR1BCYP2D6CYP2C9TSHR | |
| SCHEMBL19227677 | 0.61 | MAPT (0.71) | TSHR | |
| SCHEMBL13758821 | 0.59 | ALDH1A1 (0.40) | CYP2C9CYP2C19 | |
| SCHEMBL553085 | 0.59 | KDM4E (0.70) | — | |
| SCHEMBL5775500 | 0.59 | MTNR1A (0.42) | NQO2MTNR1AMTNR1BHTR2C | |
| SCHEMBL5812371 | 0.59 | MTNR1A (0.42) | NQO2MTNR1AMTNR1BHTR2C | |
| SCHEMBL5397777 | 0.57 | MTNR1A (0.62) | NQO2MTNR1AMTNR1B | |
| SCHEMBL11809149 | 0.56 | GLB1 (0.74) | GLB1CTRB1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058653-A1 | AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |