Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847087 | 1.00 | CYP3A4 (0.32) | CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL13843316 | 0.82 | ALOX15 (0.34) | CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL13843333 | 0.78 | CYP1A2 (0.30) | CYP3A4ALOX15 | |
| SCHEMBL13847228 | 0.77 | MTAP (0.43) | — | |
| SCHEMBL13843356 | 0.77 | MTAP (0.43) | — | |
| SCHEMBL13843313 | 0.70 | ADORA2A (0.37) | — | |
| SCHEMBL13847083 | 0.70 | ADORA2A (0.37) | — | |
| SCHEMBL10183346 | 0.67 | PI4KA (0.36) | — | |
| SCHEMBL13843349 | 0.67 | ADORA2A (0.37) | — | |
| SCHEMBL3363398 | 0.65 | NT5E (0.32) | ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534767-B2 | C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase | MERCK & CO., INC. (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080021047-A1 | C-Purine Nucleoside Analogs As Inhibitors Of Rna-Dependent Rna Viral Polymerase | MERCK SHARP & DOHME LLC | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021047-A1 | C-Purine Nucleoside Analogs As Inhibitors Of Rna-Dependent Rna Viral Polymerase | NSUN2, PNP, RNGTT | CYP3A4 2382/4885ALOX15 1572/4885TSHR 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.