SCHEMBL1384343

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1380946	0.92	SYK (0.67)	SYKEGFRJAK2LCKLYN
	SCHEMBL13007745	0.91	SYK (0.54)	SYKEGFRJAK2LCKLYN
	SCHEMBL2103358	0.87	SYK (0.62)	SYKEGFRJAK2LCKLYN
	SCHEMBL14837327	0.86	SYK (0.74)	SYKEGFRJAK2LCKLYN
	SCHEMBL2101538	0.86	SYK (0.69)	SYKEGFRJAK2LCKLYN
	SCHEMBL1384407	0.85	SYK (0.68)	SYKEGFRJAK2LCKLYN
	SCHEMBL2102264	0.85	SYK (0.62)	SYKEGFRJAK2LCKLYN
	SCHEMBL13007744	0.84	SYK (0.60)	SYKEGFRJAK2LCKLYN
	SCHEMBL1381667	0.83	SYK (0.51)	SYKEGFRJAK2LCKLYN
	SCHEMBL4000402	0.83	JAK3 (0.62)	SYKEGFRJAK2LCKLYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.