Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 20/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12244452 | 0.92 | LTA4H (0.73) | LTA4HKCNH2 | |
| SCHEMBL13844808 | 0.85 | LTA4H (0.43) | LTA4HKCNH2 | |
| SCHEMBL4693675 | 0.84 | LTA4H (0.82) | LTA4HKCNH2 | |
| SCHEMBL12245705 | 0.81 | LTA4H (0.57) | LTA4HKCNH2 | |
| SCHEMBL12222614 | 0.81 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL1906780 | 0.81 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL12240846 | 0.81 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL2539190 | 0.81 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL13844613 | 0.80 | LTA4H (0.56) | LTA4HKCNH2 | |
| SCHEMBL13844666 | 0.80 | LTA4H (0.64) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058347-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |