Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044139 | 0.71 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL3999663 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL5744006 | 0.69 | KDM4E (1.00) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL9042858 | 0.67 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL31229133 | 0.66 | MEN1 (0.48) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL7433338 | 0.66 | HTT (0.52) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL14153750 | 0.65 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL25787103 | 0.65 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL901639 | 0.65 | CYP4F2 (0.61) | SMN1; SMN2ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL31441301 | 0.64 | TSHR (0.60) | SMN1; SMN2ALDH1A1KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056520-A1 | AZABICYCLO[3.2.1]OCTANE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2009-05-07 | — | — | WO | disclosed |