Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936335 | 0.86 | MEN1 (0.49) | HTTMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL15367247 | 0.81 | MEN1 (0.60) | MAPTALDH1A1TSHRKDM4ECASP3 | |
| SCHEMBL15374432 | 0.81 | MEN1 (0.60) | MAPTALDH1A1TSHRKDM4ECASP3 | |
| SCHEMBL3095656 | 0.80 | NOTUM (0.52) | ALDH1A1SLC6A2SLC6A4SLC6A3HDAC1 | |
| SCHEMBL2191332 | 0.80 | HTT (0.49) | HTTMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL1010136 | 0.77 | ALDH1A1 (0.55) | HTTMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23484650 | 0.76 | ALDH1A1 (0.52) | HTTMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL6499815 | 0.76 | TSHR (0.66) | HTTMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL9833258 | 0.76 | MAPT (0.55) | HTTMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL7818940 | 0.74 | SLC6A2 (0.54) | MAPTSMN1; SMN2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538985-A | SIDE EFFECT REDUCTION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0668275-A1 | Pyrrolidinone derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-08-23 | — | — | EP | disclosed |